diff --git a/content/Research/datacuration_about.md b/content/Research/datacuration_about.md index 22bb1ea7f..11420f907 100644 --- a/content/Research/datacuration_about.md +++ b/content/Research/datacuration_about.md @@ -5,7 +5,7 @@ headless = true # This file represents a page section. active = true # Activate this widget? true/false weight = 100 # Order that this section will appear in. -title = "Synthetic Biology Data Curation" +title = "Accelerating Synthetic Biology Discovery through Integrated Curation" # Choose the user profile to display # This should be the username of a profile in your `content/authors/` folder. diff --git a/content/authors/Chunxiao Liao/_index.md b/content/authors/Chunxiao Liao/_index.md index 47965dabb..a20f1cc90 100644 --- a/content/authors/Chunxiao Liao/_index.md +++ b/content/authors/Chunxiao Liao/_index.md @@ -36,8 +36,8 @@ organizations: #bio: My research interests include distributed robotics, mobile computing and programmable matter. interests: -- Synthetic Biology -- Computational Biology +- Synthetic Biology, Computational Biology +- Software Engineering - Machine Learning education: @@ -95,6 +95,7 @@ user_groups: display_groups: - SynBioHub Tool - SBOLExplorer +- SeqImprove --- -Chunxiao Liao is a first-year doctoral student in the computer science department at CU Boulder, studying under Dr. Chris Myers. Before arriving in Colorado, Chunxiao completed a Master’s degree in Computer Science from the Rice University. Her research is centered around enhancing the usability and discoverability of synthetic biological data to adhere to the FAIR principles for data sharing, which stands for Findable, Accessible, Interoperable, and Reusable. More specifically, her research endeavors to apply techniques from Software Engineering, Bioinformatics, and Data Science to create an integrated curation workflow and a corresponding search methodology. +Chunxiao Liao is a second-year doctoral student in the computer science department at CU Boulder, studying under Dr. Chris Myers. Before arriving in Colorado, Chunxiao completed a Master’s degree in Computer Science from the Rice University. Her research is centered around enhancing the usability and discoverability of synthetic biological data to adhere to the FAIR principles for data sharing, which stands for Findable, Accessible, Interoperable, and Reusable. More specifically, her research endeavors to apply techniques from Software Engineering, Bioinformatics, and Data Science to create an integrated curation workflow and a corresponding search methodology. diff --git a/content/authors/NSF_Data_Curation/_index.md b/content/authors/NSF_Data_Curation/_index.md index 198bba3c1..496e64cb6 100644 --- a/content/authors/NSF_Data_Curation/_index.md +++ b/content/authors/NSF_Data_Curation/_index.md @@ -1,6 +1,6 @@ --- # Display name -title: Synthetic Biology Data Curation +title: Accelerating Synthetic Biology Discovery through Integrated Curation #Use 1 for PI, 100 for Current Postdocs, 200 for current phds, 300 for current masters, 400 for current undergrads, 800 for alum postdocs, 810 for alum phds, 820 for alum masters, and 830 for alum undergrads, 900 for tools, 1000 for projects, 900 for tools, 1000 for projects weight: 1000 @@ -58,4 +58,6 @@ user_groups: - SBKS Project --- -Synthetic biology designed systems have many applications in areas including environmental, manufacturing, sensor development, defense, and medicine. However, currently the progress and usefulness of synthetic biology is impeded by the time required for literature studies and the replication of existing but poorly documented work. The Synthetic Biology Knowledge System (SBKS) project endeavored to address these challenges by integrating data from parts repositories with information extracted from literature into a unified knowledge system. However, this form of post-hoc curation requires the extraction of knowledge from manuscript and supplemental text files after publication by curators separate from the original authors. To handle large amounts of data, machines are used to scour free text and attempt to recognize key words and work out their meaning from context. This tests the limits of named entity recognition and entity classification. Additionally, it leaves ambiguous entities that only the original authors might disambiguate. For example, yeast may refer to many different strains of yeast. Furthermore, the SBKS project also extracted sequences provided as supplemental information in publications. However, these sequences, even when they are provided, are typically poorly annotated, incomplete, and provided in non-machine readable formats. Taken together, the SBKS project demonstrated that reconstruction of this important design information through post-hoc curation is extremely noisy and error prone. \ No newline at end of file +Synthetic biology designed systems have many applications in areas including environmental, manufacturing, sensor development, defense, and medicine. However, currently the progress and usefulness of synthetic biology is impeded by the time required for literature studies and the replication of existing but poorly documented work. The Synthetic Biology Knowledge System (SBKS) project endeavored to address these challenges by integrating data from parts repositories with information extracted from literature into a unified knowledge system. However, this form of post-hoc curation requires the extraction of knowledge from manuscript and supplemental text files after publication by curators separate from the original authors. To handle large amounts of data, machines are used to scour free text and attempt to recognize key words and work out their meaning from context. This tests the limits of named entity recognition and entity classification. Additionally, it leaves ambiguous entities that only the original authors might disambiguate. For example, yeast may refer to many different strains of yeast. Furthermore, the SBKS project also extracted sequences provided as supplemental information in publications. However, these sequences, even when they are provided, are typically poorly annotated, incomplete, and provided in non-machine readable formats. Taken together, the SBKS project demonstrated that reconstruction of this important design information through post-hoc curation is extremely noisy and error prone. + +This project is founded by National Science Foundation Grants No. 2231864 \ No newline at end of file diff --git a/content/authors/SBKS/_index.md b/content/authors/SBKS/_index.md index 125a98f46..d9875109d 100644 --- a/content/authors/SBKS/_index.md +++ b/content/authors/SBKS/_index.md @@ -59,3 +59,5 @@ user_groups: --- The scientific challenge for this project is to accelerate discovery and exploration of the synthetic biology design space. In particular, many parts used in synthetic biology come from or are initially tested in a simple bacteria, E. coli, but many potential applications in energy, agriculture, materials, and health require either different bacteria or higher level organisms (yeast for example). Currently, researchers use a trial-and-error approach because they cannot find reliable information about prior experiments with a given part of interest. This process simply cannot scale. Therefore, to achieve scale, a wide range of data must be harnessed to allow confidence to be determined about the likelihood of success. The quantity of data and the exponential increase in the publications generated by this field is creating a tipping point, but this data is not readily accessible to practitioners. To address this challenge, our multidisciplinary team of biological engineers, machine learning experts, data scientists, library scientists, and social scientists will build a knowledge system integrating disparate data and publication repositories in order to deliver effective and efficient access to collectively available information; doing so will enable expedited, knowledge-based synthetic biology design research. + +This project was founded by National Science Foundation Grants No. 1939892