diff --git a/CMakeLists.txt b/CMakeLists.txt
index 30e9507b2..f0e034ae3 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -45,6 +45,7 @@ include(CheckEnvironment)
 
 include(ExternalProject)
 include(ConfigureExternalProjectVariables)
+include(EP_GeneratePatchCommand)
 
 #Variables for dependencies and update custom, updated in external projects
 set(Anima_DEPS "")
diff --git a/superbuild/ConfigureExternalProjectVariables.cmake b/superbuild/ConfigureExternalProjectVariables.cmake
index 4a11e1247..ef86c294d 100644
--- a/superbuild/ConfigureExternalProjectVariables.cmake
+++ b/superbuild/ConfigureExternalProjectVariables.cmake
@@ -35,6 +35,8 @@ set(common_cache_args
   ${MACOSX_RPATH_OPTION}
 )
 
+set(EP_PATH_SOURCE ${PROJECT_SOURCE_DIR}/External-Projects)
+
 if (CMAKE_EXTRA_GENERATOR)
   set(cmake_gen "${CMAKE_EXTRA_GENERATOR} -G ${CMAKE_GENERATOR}")
 else()
diff --git a/superbuild/EP_GeneratePatchCommand.cmake b/superbuild/EP_GeneratePatchCommand.cmake
new file mode 100644
index 000000000..db18e0d28
--- /dev/null
+++ b/superbuild/EP_GeneratePatchCommand.cmake
@@ -0,0 +1,14 @@
+## #############################################################################
+## Generate patch command for an external project. To use with ExternalProject_Add
+## #############################################################################
+function(ep_GeneratePatchCommand ep OutVar patch)
+    set(PATCH_COMMAND ${CMAKE_COMMAND}
+                      -Dep:STRING=${ep}
+                      -DANIMA_SOURCE_DIR:STRING=${CMAKE_SOURCE_DIR}
+                      -DEP_PATH_SOURCE:STRING=${EP_PATH_SOURCE}
+                      -Dpatch:STRING=${patch} 
+                      -P
+                      ${CMAKE_SOURCE_DIR}/superbuild/EP_PatcherScript.cmake)
+
+    set(${OutVar} ${PATCH_COMMAND} PARENT_SCOPE)
+endfunction()
diff --git a/superbuild/EP_PatcherScript.cmake b/superbuild/EP_PatcherScript.cmake
new file mode 100644
index 000000000..fc315370f
--- /dev/null
+++ b/superbuild/EP_PatcherScript.cmake
@@ -0,0 +1,66 @@
+## #############################################################################
+## Check if a patch should be applied and apply it if needed
+## #############################################################################
+macro(directory_count_elements ep_path elements_count_res)
+    file(GLOB RESULT ${ep_path}/*)
+    list(LENGTH RESULT ${elements_count_res})
+endmacro()
+
+function(ep_GenerateValidPatcherScript ep OutVar patch)
+    find_program(GIT_BIN NAMES git)
+
+    set(PATCHES_TO_APPLY_CUR ${ANIMA_SOURCE_DIR}/superbuild/patches/${patch})
+	directory_count_elements(${EP_PATH_SOURCE}/${ep} count)
+	
+    if(NOT ${count} EQUAL 0) #Check if external_project is already cloned
+        execute_process(COMMAND ${GIT_BIN} apply --reverse --ignore-whitespace --check ${ANIMA_SOURCE_DIR}/superbuild/patches/${patch}
+                        WORKING_DIRECTORY ${EP_PATH_SOURCE}/${ep}
+                        RESULT_VARIABLE PATCH_ALREADY_APPLIED
+                        OUTPUT_QUIET
+                        ERROR_QUIET)
+        				
+        if (PATCH_ALREADY_APPLIED EQUAL 0) #As all OS system commands: 0 is Ok, not 0 is bad.
+        	# The patch is already applied
+        	message("The patch ${patch} for the external project ${ep} is already applied")
+        	set (PATCHES_TO_APPLY_CUR "") #Then erase PATCHES_TO_APPLY_CUR
+        else()
+            execute_process(COMMAND ${GIT_BIN} apply --ignore-whitespace --check ${ANIMA_SOURCE_DIR}/superbuild/patches/${patch}
+                            WORKING_DIRECTORY ${EP_PATH_SOURCE}/${ep}
+                            RESULT_VARIABLE PATCH_APPLICABLE)
+                            #OUTPUT_QUIET
+                            #ERROR_QUIET)
+        	if(PATCH_APPLICABLE EQUAL 0) #As all OS system commands: 0 is Ok, not 0 is bad.
+    		    #Do nothing, the value is already set
+    		    message("The patch ${patch} will be applied on pre-existing ${EP_PATH_SOURCE}/${ep}")
+    		else()
+        		message("*****************************************************************************************************\n")
+        		message("***** The patch ${patch} for the external project ${ep} is NOT APPLICABLE")
+        		message("***** EP PATH    = ${EP_PATH_SOURCE}/${ep}")
+				message("***** PATCH file = ${ANIMA_SOURCE_DIR}/superbuild/patches/${patch}")
+        		message("*****************************************************************************************************\n")
+        		message(FATAL_ERROR "")
+				
+        	endif()
+        endif()
+	else()
+        message("The patch ${patch} will be applied after ${ep} cloning into ${EP_PATH_SOURCE}/${ep}")		
+    endif()
+	set(PATCHES_TO_APPLY ${PATCHES_TO_APPLY} ${PATCHES_TO_APPLY_CUR})
+
+
+    set(PATCH_COMMAND "")
+    if (NOT "${PATCHES_TO_APPLY}" STREQUAL "")
+        set(PATCH_COMMAND ${GIT_BIN} apply --ignore-whitespace ${PATCHES_TO_APPLY})
+    endif()
+
+    set(${OutVar} ${PATCH_COMMAND} PARENT_SCOPE)
+endfunction()
+
+
+ep_GenerateValidPatcherScript(${ep} patchCommand ${patch})
+
+if(patchCommand)
+  execute_process(COMMAND ${patchCommand} WORKING_DIRECTORY ${EP_PATH_SOURCE}/${ep})
+else()
+  message(DEBUG "No patch treatment for ${ep}")
+endif()
diff --git a/superbuild/ITK.cmake b/superbuild/ITK.cmake
index 569f69c64..686f5ec87 100644
--- a/superbuild/ITK.cmake
+++ b/superbuild/ITK.cmake
@@ -32,6 +32,16 @@ if (NOT DEFINED ${proj}_SRC_DIR)
   set(location GIT_REPOSITORY ${GITHUB_PREFIX}InsightSoftwareConsortium/ITK.git GIT_TAG ${tag})
 endif()
 
+## #############################################################################
+## Check if patch has to be applied
+## #############################################################################
+  
+ep_GeneratePatchCommand(ITK ITK_PATCH_COMMAND ITK.patch)
+
+## #############################################################################
+## Add external-project
+## #############################################################################
+
 ExternalProject_Add(${proj}
   ${location}
   DEPENDS ${VTK_PROJ_DEP}
@@ -40,6 +50,7 @@ ExternalProject_Add(${proj}
   CMAKE_GENERATOR ${cmake_gen}
   CMAKE_GENERATOR_PLATFORM ${CMAKE_GENERATOR_PLATFORM}
   CMAKE_ARGS ${cmake_args}
+  PATCH_COMMAND ${ITK_PATCH_COMMAND}
   BUILD_ALWAYS 1
   BINARY_DIR ${CMAKE_BINARY_DIR}/${proj}
   INSTALL_COMMAND ""
diff --git a/superbuild/patches/ITK.patch b/superbuild/patches/ITK.patch
new file mode 100644
index 000000000..63d3545e6
--- /dev/null
+++ b/superbuild/patches/ITK.patch
@@ -0,0 +1,12 @@
+unchanged:
+--- a/Modules/Filtering/MathematicalMorphology/include/itkMathematicalMorphologyEnums.h
++++ b/Modules/Filtering/MathematicalMorphology/include/itkMathematicalMorphologyEnums.h
+@@ -19,6 +19,7 @@
+ #define itkMathematicalMorphologyEnums_h
+ 
+ #include <iostream>
++#include <cstdint>
+ #include "ITKMathematicalMorphologyExport.h"
+ 
+ 
+ 
\ No newline at end of file