diff --git a/.github/workflows/tests-e2e.yml b/.github/workflows/tests-e2e.yml
index 10fe52a66cfb..4ab3330d721a 100644
--- a/.github/workflows/tests-e2e.yml
+++ b/.github/workflows/tests-e2e.yml
@@ -146,6 +146,16 @@ jobs:
             wp: 'latest'
             snapshots: true
             shard: '2/2'
+          - browser: 'chrome'
+            wp: '6.6-RC1'
+            snapshots: false
+            shard: '1/2'
+            experimental: true
+          - browser: 'chrome'
+            wp: '6.6-RC1'
+            snapshots: false
+            shard: '2/2'
+            experimental: true
 
     steps:
       - name: Harden Runner
diff --git a/packages/e2e-test-utils/src/publishPost.js b/packages/e2e-test-utils/src/publishPost.js
index 58923d01f2e9..bc67f63b8470 100644
--- a/packages/e2e-test-utils/src/publishPost.js
+++ b/packages/e2e-test-utils/src/publishPost.js
@@ -67,9 +67,12 @@ async function publishPost() {
     () =>
       wp.data.select('core/editor').getEditedPostAttribute('status') ===
         'publish' &&
-      document.querySelector(
+      (document.querySelector(
         '.editor-post-publish-button[aria-disabled="true"]'
-      ).textContent === 'Update'
+      ).textContent === 'Update' ||
+        document.querySelector(
+          '.editor-post-publish-button[aria-disabled="true"]'
+        ).textContent === 'Save')
   );
 
   // The first time around the selector might return undefined.
diff --git a/packages/e2e-tests/src/config/bootstrap.js b/packages/e2e-tests/src/config/bootstrap.js
index 3dcc996e07cf..ca7a15cac79f 100644
--- a/packages/e2e-tests/src/config/bootstrap.js
+++ b/packages/e2e-tests/src/config/bootstrap.js
@@ -126,6 +126,9 @@ const ALLOWED_ERROR_MESSAGES = [
   // Coming from <amp-story-player>
   // See https://github.com/ampproject/amphtml/blob/413457c3598f8c6694ca4ee7b83a5d84f9b9f00c/src/amp-story-player/amp-story-player-impl.js#L562
   "Unrecognized feature: 'web-share'",
+
+  // This is a known issue in core.
+  'You are importing createRoot from "react-dom" which is not supported.',
 ];
 
 export function addAllowedErrorMessage(message) {
diff --git a/readme.txt b/readme.txt
index 7c049a7d9f1e..155b36f101fa 100644
--- a/readme.txt
+++ b/readme.txt
@@ -1,7 +1,7 @@
 === Web Stories ===
 
 Contributors:      google
-Tested up to:      6.5
+Tested up to:      6.6
 Requires at least: 6.4
 Stable tag:        V.V.V
 License:           Apache-2.0