diff --git a/be/issue/src/main/java/codesquad/issueTracker/issue/controller/IssueController.java b/be/issue/src/main/java/codesquad/issueTracker/issue/controller/IssueController.java
index 0df65ada4..68eb1cda6 100644
--- a/be/issue/src/main/java/codesquad/issueTracker/issue/controller/IssueController.java
+++ b/be/issue/src/main/java/codesquad/issueTracker/issue/controller/IssueController.java
@@ -15,6 +15,7 @@
 
 import codesquad.issueTracker.global.common.ApiResponse;
 import codesquad.issueTracker.issue.dto.IssueWriteRequestDto;
+import codesquad.issueTracker.issue.dto.ModifyAssigneeRequestDto;
 import codesquad.issueTracker.issue.dto.ModifyIssueContentRequestDto;
 import codesquad.issueTracker.issue.dto.ModifyIssueContentResponseDto;
 import codesquad.issueTracker.issue.dto.ModifyIssueStatusRequestDto;
@@ -70,4 +71,10 @@ public ApiResponse<String> deleteIssues(@PathVariable Long id) {
 		issueService.delete(id);
 		return ApiResponse.success(SUCCESS.getStatus(), SUCCESS.getMessage());
 	}
+
+	@PatchMapping("/issues/{id}/assignees")
+	public ApiResponse<String> patchAssignees(@PathVariable Long id, @RequestBody ModifyAssigneeRequestDto request) {
+		issueService.modifyAssignees(id, request);
+		return ApiResponse.success(SUCCESS.getStatus(), SUCCESS.getMessage());
+	}
 }
diff --git a/be/issue/src/main/java/codesquad/issueTracker/issue/repository/IssueRepository.java b/be/issue/src/main/java/codesquad/issueTracker/issue/repository/IssueRepository.java
index 152c72afd..48f3e9be3 100644
--- a/be/issue/src/main/java/codesquad/issueTracker/issue/repository/IssueRepository.java
+++ b/be/issue/src/main/java/codesquad/issueTracker/issue/repository/IssueRepository.java
@@ -108,4 +108,12 @@ public Long delete(Long id) {
 		jdbcTemplate.update(sql, parameters);
 		return id;
 	}
+
+	public Long resetAssignees(Long issueId) {
+		String sql = "DELETE FROM assignees WHERE issue_id = :issueId";
+		SqlParameterSource parameterSource = new MapSqlParameterSource()
+			.addValue("issueId", issueId);
+		jdbcTemplate.update(sql, parameterSource);
+		return issueId;
+	}
 }
diff --git a/be/issue/src/main/java/codesquad/issueTracker/issue/service/IssueService.java b/be/issue/src/main/java/codesquad/issueTracker/issue/service/IssueService.java
index 9fd283750..276c59624 100644
--- a/be/issue/src/main/java/codesquad/issueTracker/issue/service/IssueService.java
+++ b/be/issue/src/main/java/codesquad/issueTracker/issue/service/IssueService.java
@@ -14,6 +14,7 @@
 import codesquad.issueTracker.global.exception.ErrorCode;
 import codesquad.issueTracker.issue.domain.Issue;
 import codesquad.issueTracker.issue.dto.IssueWriteRequestDto;
+import codesquad.issueTracker.issue.dto.ModifyAssigneeRequestDto;
 import codesquad.issueTracker.issue.dto.ModifyIssueContentRequestDto;
 import codesquad.issueTracker.issue.dto.ModifyIssueContentResponseDto;
 import codesquad.issueTracker.issue.dto.ModifyIssueStatusRequestDto;
@@ -124,4 +125,24 @@ public Long delete(Long id) {
 		return deletedId;
 
 	}
+
+	@Transactional
+	public Long modifyAssignees(Long id, ModifyAssigneeRequestDto request) {
+		validateExistIssue(id);
+		List<Long> assignees = request.getAssignees();
+		duplicatedId(assignees);
+		if (assignees != null) {
+			for (Long assigneeId : assignees) {
+				userService.validateUserId(assigneeId);
+			}
+			issueRepository.resetAssignees(id);
+			for (Long assigneeId : assignees) {
+				issueRepository.insertAssignees(id, assigneeId);
+			}
+			return id;
+		}
+		issueRepository.resetAssignees(id);
+		return id;
+	}
+
 }