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DESCRIPTION
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DESCRIPTION
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Package: posibatch
Title: Adjust for positional and batch effects using ComBat
Version: 1.0
Author: Chuan Jiao <[email protected]>, Chao Chen <[email protected]>, Chunyu Liu <[email protected]>
Description: posibatch allows users to adjust for positional effects and batch effects in Illumina Beadchips.
Positional effects means the same sample in different physical positions on the array could be measured
as different methylation or expression levels, and batch effects. Batch effects are sub-groups of
measurements that have qualitatively different behaviour across conditions and are unrelated to
the biological or scientific variables in a study. It uses either parametric or non-parametric
empirical Bayes frameworks for adjusting data for positional effects and batch effects.
Users are returned an expression or methylation matrix that has been corrected for position effects and
batch effects.
Maintainer: Chuan Jiao <[email protected]>, Chao Chen <[email protected]>, Chunyu Liu <[email protected]>
Depends: R (>= 2.8), sva, lme4
License: GPL-2
biocViews: Microarray, MethylationArray, StatisticalMethod,
Preprocessing, MultipleComparison, Sequencing, RNASeq,
BatchEffect, PositionalEffect, Normalization
NeedsCompilation: yes
RoxygenNote: 6.0.1
Packaged: 2017-07-07 11:42:30 UTC; J