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Query to find proteins with high average disorder content #25

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AlasdairGray opened this issue May 20, 2022 · 2 comments
Open

Query to find proteins with high average disorder content #25

AlasdairGray opened this issue May 20, 2022 · 2 comments
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@AlasdairGray
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Which proteins have high average protein disorder content (>95%, >50% or >0%) in MobiDB, but not yet annotated manually in DisProt.

Note that this query requires a new property to be added to the MobiDB markup.

@AlasdairGray AlasdairGray self-assigned this May 20, 2022
@AlasdairGray
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@ivanmicetic do you remember what the property is that you were adding in to make this query feasible?

We'll need to make sure that it comes through the conversion process and is stored in the IDP-KG.

@ivanmicetic
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Current MobiDB's markup has a property for Protein disorder content, I don't remember when it was added. Probably after the crawls. The current markup is like this:

"hasSequenceAnnotation": [
    {
      "@type": "SequenceAnnotation",
      "@id": "https://mobidb.org/O75475#prediction-disorder-content-mobidb_lite",
      "sequenceLocation": {
        "@type": "SequenceRange",
        "rangeStart": 1,
        "rangeEnd": 530
      },
      "additionalProperty": {
        "@type": "PropertyValue",
        "name": "Protein disorder content",
        "propertyID": {
          "@id": "https://disprot.org/assets/data/IDPO_v0.2.owl#IDPO:00499"
        },
        "value": 0.655
      },
      "description": "Protein disorder content predicted by MobiDB-lite"
    },
...
]

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