diff --git a/projects/plugins/jetpack/changelog/rnmobile-detect-invalid-urls b/projects/plugins/jetpack/changelog/rnmobile-detect-invalid-urls
new file mode 100644
index 0000000000000..a0ac3ba002b1f
--- /dev/null
+++ b/projects/plugins/jetpack/changelog/rnmobile-detect-invalid-urls
@@ -0,0 +1,4 @@
+Significance: patch
+Type: other
+
+RNMobile: Detect and avoid invalid media URLs in VideoPress v5 block
diff --git a/projects/plugins/jetpack/extensions/blocks/videopress/edit.native.js b/projects/plugins/jetpack/extensions/blocks/videopress/edit.native.js
index 63e35295f364d..e81a5d0df351b 100644
--- a/projects/plugins/jetpack/extensions/blocks/videopress/edit.native.js
+++ b/projects/plugins/jetpack/extensions/blocks/videopress/edit.native.js
@@ -206,7 +206,7 @@ class VideoPressEdit extends Component {
 	onSelectURL( url ) {
 		const { createErrorNotice, setAttributes, onReplace } = this.props;
 
-		if ( isURL( url ) ) {
+		if ( isURL( url ) && /^https?:/.test( getProtocol( url ) ) ) {
 			// Check if there's an embed block that handles this URL.
 			const embedBlock = createVideoPressEmbedBlock( {
 				attributes: { url },