diff --git a/pyproject.toml b/pyproject.toml
index 4b8cbd3800..4d1b5e2ee9 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -3,7 +3,7 @@ requires = [
   "setuptools",
   "setuptools_scm>=6.2",
   "wheel",
-  "cython",
+  "cython>=3.0",
   "numpy>=2.0.0rc1"
 ]
 
diff --git a/setup.py b/setup.py
index 4dc2b0da48..8420794546 100644
--- a/setup.py
+++ b/setup.py
@@ -127,6 +127,9 @@ def check_rsl_path(rsl_lib_path, rsl_include_path):
 rsl_lib_path = os.path.join(rsl_path, "lib")
 rsl_include_path = os.path.join(rsl_path, "include")
 
+# Set a variable for the numpy flags to add to cython
+define_macros = [("NPY_NO_DEPRECATED_API", "NPY_1_7_API_VERSION")]
+
 # build the RSL IO and FourDD dealiaser if RSL is installed
 if check_rsl_path(rsl_lib_path, rsl_include_path):
     fourdd_sources = [
@@ -146,6 +149,7 @@ def check_rsl_path(rsl_lib_path, rsl_include_path):
         library_dirs=[rsl_lib_path],
         include_dirs=[rsl_include_path, "pyart/correct/src"] + [get_include()],
         runtime_library_dirs=[rsl_lib_path],
+        define_macros=define_macros,
     )
 
     # Cython wrapper around RSL io
@@ -156,6 +160,7 @@ def check_rsl_path(rsl_lib_path, rsl_include_path):
         library_dirs=[rsl_lib_path],
         include_dirs=[rsl_include_path] + [get_include()],
         runtime_library_dirs=[rsl_lib_path],
+        define_macros=define_macros,
     )
 
     extensions.append(extension_rsl)
@@ -170,6 +175,7 @@ def check_rsl_path(rsl_lib_path, rsl_include_path):
     "pyart.__check_build._check_build",
     sources=["pyart/__check_build/_check_build.pyx"],
     include_dirs=[get_include()],
+    define_macros=define_macros,
 )
 
 extensions.append(extension_check_build)
@@ -179,22 +185,30 @@ def check_rsl_path(rsl_lib_path, rsl_include_path):
     "pyart.correct._fast_edge_finder",
     sources=["pyart/correct/_fast_edge_finder.pyx"],
     include_dirs=[get_include()],
+    define_macros=define_macros,
 )
 
 extension_1d = Extension(
     "pyart.correct._unwrap_1d",
     sources=["pyart/correct/_unwrap_1d.pyx"],
     include_dirs=[get_include()],
+    define_macros=define_macros,
 )
 
 unwrap_sources_2d = ["pyart/correct/_unwrap_2d.pyx", "pyart/correct/unwrap_2d_ljmu.c"]
 extension_2d = Extension(
-    "pyart.correct._unwrap_2d", sources=unwrap_sources_2d, include_dirs=[get_include()]
+    "pyart.correct._unwrap_2d",
+    sources=unwrap_sources_2d,
+    include_dirs=[get_include()],
+    define_macros=define_macros,
 )
 
 unwrap_sources_3d = ["pyart/correct/_unwrap_3d.pyx", "pyart/correct/unwrap_3d_ljmu.c"]
 extension_3d = Extension(
-    "pyart.correct._unwrap_3d", sources=unwrap_sources_3d, include_dirs=[get_include()]
+    "pyart.correct._unwrap_3d",
+    sources=unwrap_sources_3d,
+    include_dirs=[get_include()],
+    define_macros=define_macros,
 )
 
 extensions.append(extension_edge_finder)
@@ -207,12 +221,14 @@ def check_rsl_path(rsl_lib_path, rsl_include_path):
     "pyart.io._sigmetfile",
     sources=["pyart/io/_sigmetfile.pyx"],
     include_dirs=[get_include()],
+    define_macros=define_macros,
 )
 
 extension_nexrad = Extension(
     "pyart.io.nexrad_interpolate",
     sources=["pyart/io/nexrad_interpolate.pyx"],
     include_dirs=[get_include()],
+    define_macros=define_macros,
 )
 
 extensions.append(extension_sigmet)
@@ -224,18 +240,21 @@ def check_rsl_path(rsl_lib_path, rsl_include_path):
     sources=["pyart/map/ckdtree.pyx"],
     include_dirs=[get_include()],
     libraries=libraries,
+    define_macros=define_macros,
 )
 
 extension_load_nn = Extension(
     "pyart.map._load_nn_field_data",
     sources=["pyart/map/_load_nn_field_data.pyx"],
     include_dirs=[get_include()],
+    define_macros=define_macros,
 )
 
 extension_gate_to_grid = Extension(
     "pyart.map._gate_to_grid_map",
     sources=["pyart/map/_gate_to_grid_map.pyx"],
     libraries=libraries,
+    define_macros=define_macros,
 )
 
 extensions.append(extension_ckd)
@@ -245,7 +264,9 @@ def check_rsl_path(rsl_lib_path, rsl_include_path):
 
 # Retrieve pyx extensions
 extension_kdp = Extension(
-    "pyart.retrieve._kdp_proc", sources=["pyart/retrieve/_kdp_proc.pyx"]
+    "pyart.retrieve._kdp_proc",
+    sources=["pyart/retrieve/_kdp_proc.pyx"],
+    define_macros=define_macros,
 )
 
 extensions.append(extension_kdp)